A Platform, a Premium Strain, and Cutting-Edge Screening 

Yielding Optimal Therapeutic Protein Expression, Uniquely Tailored to Each Project

 

At KBI Biopharma, our PUREplatform is everything you need to make a therapeutic protein. PUREplatform contains plasmids, strains, media, and a fermentation process that all fit together into a service package catered to your needs. 

KBI has redefined what it means to have an optimal expression strain, with 10+ years of therapeutic protein development rolled into one platform. PUREplatform starts in microbial cell line development (CLD) with our proprietary PUREcoli™ strain that includes unique substrains, designed specifically to quickly feed upstream process development and late-stage manufacturing with pre-established process elements.

• Features our PUREcoli™ cell line, our proprietary high-producing E. coli cell line, expertly paired with PUREplasmids™ and PUREmedia™ available in 8, 24, 48, and 96 screening packages
  
• Designed for secreted proteins, including antibody fragments (FAbs), inclusion bodies (IBs), and soluble intracellular molecules
• Robust high-throughput fermentation conditions that scale from 1 mL microfermentations  to 2,000 L
• Built for small- and large-scale cGMP manufacturing
• Well-versed in first in human (FIH) studies, late-stage manufacturing, and commercialization

Strain development was just the start of our mission. To support biopharmaceutical development and fermentation production, our platform targets product quality, safety, and titer across therapeutic proteins and at scale.

Just one way KBI is Doing More with Microbes from early optimization through to late-stage and commercial manufacturing.

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